CL VS. IOL CORRECTION OF MONOCULAR APHAKIA. The visual outcomes and adverse events of contact lens with primary intraocular lens (IOL) correction of monocular aphakia during infancy were compared by the Infant Aphakia Treatment Study Group. In a randomized, multicenter clinical trial, 114 infants with a unilateral congenital cataract underwent cataract surgery between 1 to 6 months of age either with or without primary IOL implantation. Contact lenses were used to correct aphakia in patients who did not receive IOLs. There was no significant difference in grating visual acuity at age 1 between the IOL and contact lens groups; however, additional intraocular operations were performed more frequently in the IOL group.
BETTER VISION TREATMENT FOR DIABETIC MACULAR EDEMA. Diabetic Retinopathy Clinical Research Network has shown that ranibizumab eye injections, often in combination with laser treatment, result in better vision than laser treatment alone for diabetes-associated swelling of the retina. The participants consisted of 691 people diagnosed with Type 1 or 2 diabetes and macular edema. Nearly 50% of patients who received this new treatment experienced substantial visual improvement after one year, compared with 28% who received the standard laser treatment alone.
EARLY TREATMENT FOR RETINOPATHY PREMATURITY. The Early Treatment for Retinopathy of Prematurity Cooperative Group compared visual acuity at age 6 in eyes that received early treatment for high-risk pre-threshold retinopathy of prematurity with conventionally managed eyes. With use of the Type 1 and Type 2 clinical algorithm, six-year visual acuity results showed a benefit for Type 1 eyes treated early but not for Type 2 eyes. Compared with conventionally managed eyes, early treated eyes had a significantly better structural outcome with no increased risk of ocular complications.
STRABISMUS COMMON IN PATHOLOGIC MYOPIA. A high prevalence of horizontal and vertical strabismus in patients with pathologic myopia was confirmed by Tokyo Medical and Dental University Graduate School. Among the 636 highly myopic patients, 82% had orthophoria, 13% had exotropia, and 5% had esotropia at near distance. At long distance, 87% had orthophoria, 9% had exotropia, and 5% had esotropia. Vertical heterotropia was seen in 16% of patients.
COLOR VISION INDICATOR FOR VISUAL LOSS. The Meir Medical Center and Sackler Faculty of Medicine divided 250 patients into four groups according to the etiology of visual loss: optic neuropathies, macular diseases, media opacities, and amblyopia. Patients with optic neuropathy were most likely and patients with amblyopia were the least expected to have a significant color vision loss. Those with optic neuropathy had worse average color vision compared to patients in other three categories. Testing concluded that diseases of the optic nerve do affect color vision earlier and more profoundly than other diseases.